In this capstone project course, we'll compare genome sequences of COVID-19 mutations to identify potential areas a drug therapy can look to target. The first step in drug discovery involves identifying target subsequences of theirs genome to target. We'll start by comparing the genomes of virus mutations to look for similarities. Then, we'll perform PCA to cut down our number of dimensions and identify the most common features. Next, we'll use K-means clustering in Python to find the optimal number of groups and trace the lineage of the virus. Finally, we'll predict similarity between the sequences and use this to pick a target subsequence. Throughout the course, each section will consist of a programming assignment coupled with a guide video and helpful hints. By the end, you'll be well on your way to discovering ways to combat disease with genome sequencing.

Capstone Project: Advanced AI for Drug Discovery
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Capstone Project: Advanced AI for Drug Discovery
This course is part of AI for Scientific Research Specialization

Instructor: LearnQuest Network
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What you'll learn
Analyzing genome sequences to find similarities and identify target subsequences using predctive models.
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Novartis

Novartis

University of California San Diego
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