Most great ideas never become commercial successes — and the odds of turning an invention into a profitable business are statistically worse than winning the lottery. This course reframes the innovation challenge with a counterintuitive insight: the biggest barriers to innovation are not cultural or psychological, but structural. Learners will explore the five key internal barriers that prevent inventions from reaching the marketplace — super specialization, inflexible operations, insufficient resources, regulatory constraints, and limited market access — and discover proven strategies to overcome each one. Through real-world case studies from IBM, Motorola, Texas Instruments, and others, learners will understand why even well-funded, well-intentioned companies fail to commercialize their best ideas, and what it takes to break through the structural resistance that stands between innovation and market success.